Genomics Research
Genomics Research
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Genomics Research

Biosciences

  • TCR/BCR Immunome Repertoire Profiling
  • Tumor & Immune Microenvironment Analysis
  • RNA-Seq & Transcriptomics
  • Viral Integration & Off-Target Analysis
  • Custom Tumor Panels & Liquid Biopsy

As a leading biomarker service provider, we specialize in cutting-edge genomic research to empower precision medicine, immunotherapy development, and disease mechanism studies. Our high-throughput sequencing and advanced bioinformatics platforms deliver accurate, reproducible, and clinically actionable insights, enabling researchers and biopharma partners to decode complex biological systems.

We offer comprehensive genomic research solutions, including but not limited to:

TCR/BCR Immunome Repertoire Profiling

Tumor & Immune Microenvironment Analysis

RNA-Seq & Transcriptomics

Viral Integration & Off-Target Analysis

Custom Tumor Panels & Liquid Biopsy

TCR/BCR Immunome Repertoire Profiling

  • TCR-β sequencing (DNA-level) for high-precision clonal quantification.
  • B-cell receptor (BCR) analysis to study humoral immunity.
  • Applications: Cancer immunotherapy monitoring, autoimmune disease research, infectious disease immune response tracking.

Tumor & Immune Microenvironment Analysis

  • Tumor-infiltrating lymphocyte (TIL) profiling – Assess clonal expansion and dynamics.
  • Neoantigen prediction & immune evasion studies.
  • Single-cell immune profiling (optional integration with scRNA-seq).

RNA-Seq & Transcriptomics

  • Bulk and single-cell RNA sequencing for gene expression, splicing, and fusion analysis.
  • Immune cell deconvolution – Quantify immune subsets in tumor/stromal tissues.

Viral Integration & Off-Target Analysis

  • Detect unintended genomic alterations in cell/gene therapies (e.g., CAR-T, CRISPR).
  • Monitor viral vector integration sites for safety assessment.

Custom Tumor Panels & Liquid Biopsy

  • Targeted NGS panels for somatic mutation, MSI, TMB, and CNV analysis.
  • ctDNA-based monitoring for minimal residual disease (MRD) detection.

Technical Advantages

  • Genomic DNA-Based TCR Profiling: It enables absolute quantification of all T-cell clonotypes, overcoming variability associated with RNA degradation and expression fluctuations.
  • Multiplex PCR with Optimized Primer Design: It covers all VDJ gene families using 60+ primers, ensuring comprehensive CDR3 region amplification.
  • Bias Correction Model: It incorporates a proprietary correction system to reduce PCR amplification bias and maintain quantitative accuracy and reproducibility.
  • High Sensitivity and Resolution: Capable of detecting low-frequency clones and subtle shifts in immune repertoire, critical for monitoring immunotherapeutic interventions.

Whether you're investigating T-cell dynamics in cancer, assessing immune status in infectious diseases, or validating gene therapy safety, our Genomic Research Services are designed to accelerate your discoveries and deliver actionable insights. Please feel free to contact us for more information.

Trust Us for Your Genomics Research Needs.

Our company offers advanced genomics research services to support a wide range of research and development efforts in the pharmaceutical, biotechnology, materials science and chemical industries.

Please kindly note that our products and services are for research use only.